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	Provedor de dados Biol. Res. (1) BJMBR (1) Autor Oviedo-Solís,Cecilia I. (1) Ramírez-Emiliano,Joel (1) Sandoval-Salazar,Cuauhtemoc (1) Solís-Ortiz,Martha Silvia (1) Trejo-Bahena,Aurora (1) Palavra-chave Frontal cortex (2) Acetylcholinesterase (1) GABA (1) High-fat diet (1) Hippocampus (1) Obesity (1) REM sleep deprivation (1) Mais... Tipo do documento Info:eu-repo/semantics/other (1) Journal article (1) Ano 2016 (1) 1997 (1) País Brazil (1) Chile (1) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última A high-fat diet decreases GABA concentration in the frontal cortex and hippocampus of rats Biol. Res. Sandoval-Salazar,Cuauhtemoc; Ramírez-Emiliano,Joel; Trejo-Bahena,Aurora; Oviedo-Solís,Cecilia I.; Solís-Ortiz,Martha Silvia. BACKGROUND: It has been proposed that the γ-aminobutyric acid (GABA) plays a key role in the regulation of food intake and body weight by controlling the excitability, plasticity and the synchronization of neuronal activity in the frontal cortex (FC). It has been also proposed that the high-fat diet (HFD) could disturb the metabolism of glutamate and consequently the GABA levels, but the mechanism is not yet clearly understood. Therefore, the aim of this study was to investigate the effect of a HFD on the GABA levels in the FC and hippocampus of rats RESULTS: The HFD significantly increased weight gain and blood glucose levels, whereas decreased the GABA levels in the FC and hippocampus compared with standard diet-fed rats CONCLUSIONS: HFD... Tipo: Journal article Palavras-chave: Obesity; GABA; Frontal cortex; Hippocampus; High-fat diet. Ano: 2016 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602016000100015 Rapid eye movement (REM) sleep deprivation reduces rat frontal cortex acetylcholinesterase (EC 3.1.1.7) activity BJMBR Rapid eye movement (REM) sleep deprivation induces several behavioral changes. Among these, a decrease in yawning behavior produced by low doses of cholinergic agonists is observed which indicates a change in brain cholinergic neurotransmission after REM sleep deprivation. Acetylcholinesterase (Achase) controls acetylcholine (Ach) availability in the synaptic cleft. Therefore, altered Achase activity may lead to a change in Ach availability at the receptor level which, in turn, may result in modification of cholinergic neurotransmission. To determine if REM sleep deprivation would change the activity of Achase, male Wistar rats, 3 months old, weighing 250-300 g, were deprived of REM sleep for 96 h by the flower-pot technique (N = 12). Two additional... Tipo: Info:eu-repo/semantics/other Palavras-chave: REM sleep deprivation; Frontal cortex; Acetylcholinesterase. Ano: 1997 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1997000500012 Registros recuperados: 2 Primeira ... 1 ... Última

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